Friday, May 27, 2011

Stem Cells

Stem Cells - An Overview - Prof. Colin McGuckin
http://www.youtube.com/watch?v=kjI1c1P81pI

http://en.wikipedia.org/wiki/List_of_Greek_and_Latin_roots_in_English
Excerpts:
1)
nov-newLatinnovusinnovation, nova
2)
san-healthyLatinsanusinsane, sanity



http://www.fictionalley.org/authors/v_m_bell/SN.html
Excerpt:

Sanguis Novus by V.M. Bell

Rating: PG
"Happy is the house that shelters a friend." - Ralph Waldo Emerson. Lily Evans has yearned all her life for home and happiness, and when she receives her Hogwarts letter, it offers her everything she has ever wished for. But beneath this promising facade, there lies something darker and more complex than she ever could have imagined.
Will Lily be ready to handle the pressures a new world can bring?
More importantly, will she find someone with whom to share the burden?


http://www.phgfoundation.org/news/4656/
Excerpt:

Commercial cord blood banking controversy in Ireland

9 June 2009   |   By Dr Philippa Brice   |   News story
Following on from a report earlier this year that some UK hospitals were refusing to allow the harvesting of umbilical cord blood at birth by health professionals licensed by commercial operators (see previous news), the Times newspaper has now reported that parents of babies born in Ireland may sue Irish health authorities for preventing the collection of umbilical cord blood cells at birth. At present, collection can only take place in private hospitals, and cord blood must be stored in tissue banks overseas because there are no public or private Irish cord blood banks.
Professor Colin McGuckin, stem cell specialist and president of Novus Sanguis, an international research consortium on cord blood and adult stem cell research, is quoted as saying that Ireland was being “left way behind the rest of Europe and the world” and that storing cord blood as a potential future source of therapeutic stem cells for the new baby, whilst not a guaranteed cure, could be “hugely beneficial” (see Times news report). Although tissue-matched stem cells from cord blood can be used for the treatment of various rare diseases, and are considered to hold significant promise for a range of others, the benefits of stem cell therapeutics remain non-proven for most conditions. The argument for storing cord blood is that a precise tissue match would be perfect for future stem cell treatments of the child from whom the sample is taken, should these become available and the child develop a relevant disease in later life.

http://fr.wikipedia.org/wiki/Novus_Sanguis
Excerpt:
Novus Sanguis est un consortium de recherche international sur le sang de cordon ombilical, en cours de création. Fondé par l'équipe du professeur Colin Mc Guckin du Centre de Recherche sur le Sang de cordon ombilical et de médecine régénérative de l’université de Newcastle en Grande-Bretagne, et la Fondation Jérôme Lejeune à Paris, Novus Sanguis réunira plusieurs laboratoires du monde entier pour travailler étroitement en réseau.
Le Pr Mc Guckin, avec son collaborateur français, le Dr Nicolas Forraz, est le premier au monde à avoir démontré (en 2005) l’existence de cellules pluripotentes dans le sang de cordon, c’est-à-dire qui ont la propriété de se transformer en de nombreux tissus différents.
Le consortium Novus Sanguis réunira scientifiques et industriels pour travailler ensemble.

http://kidshealth.org/parent/_cancer_center/treatment/cord_blood.html  Umbilical Cord Banking

http://en.wikipedia.org/wiki/Cord_blood_bank
Excerpt:
Cord blood bank
From Wikipedia, the free encyclopedia
Jump to: navigation, search
A cord blood bank is a facility which stores umbilical cord blood for future use. Both private and public cord blood banks have developed since the mid- to late-1990s in response to the potential for cord blood transplants in treating diseases of the blood and immune systems.
Public banks accept donations to be used for anyone in need. Unlike private cord blood banking, public cord blood banking is supported by the medical community.[1][2][3] However, there are very strict regulations which public banks need to follow in order to enable the donated units to be added to a registry. Generally, an expectant mother interested in donation should contact the bank before the 34th week of pregnancy. The National Marrow Donor Program has a list of public cord blood banks on their website. Once the blood is donated, it loses all identifying information after a short period of initial testing. Families are not able to retrieve their own blood after it has been donated, but, as discussed below, it is very unlikely that they would be able to use the sample themselves.
Private banks store cord blood with a link to the identity of the donor, so that the family may retrieve it later if it is needed. The parents have custody of the cord blood until the child is an adult. The cord blood might someday be needed by the donor baby, or it could be used by a relative who is a close enough match to receive a transplant from the donor (typically a sibling). Private banks charge a fee of around $1000–$2000 to preserve the harvested cord blood for family biological insurance. Private banks have been criticized for aggressive marketing campaigns to expectant parents.
In the United States, the Food and Drug Administration regulates cord blood under the category of “Human Cells, Tissues, and Cellular and Tissue Based-Products.” The Code of Federal Regulations under which the FDA regulates public and private cord blood banks is Title 21 Section 1271. Both public and private cord blood banks are eligible for voluntary accreditation with either the American Association of Blood Banks AABB or the Foundation for the Accreditation of Cellular Therapy FACT. Potential clients can check the current accreditation status of banks from the AABB list of accredited cord blood banks or the FACT search engine of accredited cord blood banks. Other countries also have regulations pertaining to cord blood.
Cord blood contains hematopoietic stem cells, progenitor cells which can form red blood cells, white blood cells and platelets. Cord blood cells are currently used to treat blood and immune system related genetic diseases, cancers, and blood disorders. Medical critics of routine cord blood collection emphasize that, if neonatal cord blood is so physiologically valuable, it is of great benefit for the neonate to receive upon birth.


http://www.epigee.org/fetal/post_bleeding.html
Excerpt:



Postpartum Bleeding

Now that baby has arrived, you are probably waiting for your body to begin to go back to normal. Well, your body is on its way, but "normal" may take some time to achieve. For the first few weeks, for instance, you will have to deal with postpartum bleeding. Postpartum bleeding is a completely normal part of the postpartum period and, for the most part, goes away on its own. However, bleeding during the postpartum period can sometimes indicate underlying health complications.


Lochia

Lochia is the name given to postpartum bleeding. Every woman who delivers a child, either vaginally or through cesarean section, will experience this type of bleeding. It is the way in which your body expels excess mucus, placental tissue, and blood after giving birth.
Lochia is very similar to the bleeding you experience during your menstrual period, however, it is much heavier. It typically begins in the hours immediately following birth and usually continues for two or three weeks. However, in some women lochia can last for up to six weeks.
Symptoms of Lochia
Lochia usually begins as a bright red discharge from the vagina. This blood typically continues to be bright red in color for between four and ten days. After ten days, your lochia will become a pink color, eventually changing to a yellowish-white color. This blood flow may be constant and even, or it may be expelled in intermittent gushes. Lochia may also be accompanied by numerous small blood clots, about the size of a grape.
Dealing with Lochia
Postpartum bleeding can sometimes be annoying to contend with, however, there are some ways to make the going easier:

  • Rest as much as you can, and avoid excess standing and walking (this will exacerbate the blood flow).
  • Use heavy duty maxi pads to soak up the blood.
  • Do not use tampons for at least six weeks after pregnancy. Tampons can introduce bacteria in to the vagina and uterus, causing infection.

Warning Signs
Typically, lochia is not the result of any health complication and will end on its own when your body is ready. However, some women do experience problems with their postpartum bleeding. If you experience any of the following signs, call your health care provider or visit your nearest emergency room:

  • bright red discharge for more than seven days after birth
  • discharge that smells bad
  • fever and chills
  • abnormally heavy bleeding (in which a maxi pad is soaked in less than one hour)


Postpartum Hemorrhaging

Postpartum hemorrhaging is a more severe type of post-pregnancy bleeding. If you lose more than 500 mL of blood after a vaginal birth, or more than 1000 mL after a cesarean section birth, you are classified as having postpartum hemorrhaging. Postpartum hemorrhaging can be a very dangerous condition, and is associated with various complications including heavy blood loss and even maternal death.
Postpartum hemorrhaging occurs in between 1% and 10% of all pregnancies in the United States. It usually begins in the 24 hours immediately following childbirth (early postpartum hemorrhage), however, it can occur anytime during the six weeks following delivery (delayed postpartum hemorrhage).
What Causes Postpartum Hemorrhaging?
The most common cause of postpartum hemorrhage occurs when the uterus does not contract after birth. This allows the uterus to continue bleeding, and can result in massive blood loss. Other causes of postpartum hemorrhage include:

  • failure to pass all of your placenta
  • forced removal of the placenta
  • trauma to the uterus, cervix, or vagina during delivery

Who's At Risk for Postpartum Hemorrhaging?
Every woman is at risk for developing postpartum hemorrhage. However, there are certain factors that will increase your risk. These include:


Symptoms of Postpartum Hemorrhaging
It is extremely important that every new mother knows how to recognize the symptoms of postpartum hemorrhage. Quick treatment is essential in order to prevent massive blood loss and death. Symptoms include:

  • massive blood loss
  • passing large clots
  • dizziness, lightheadedness, or fatigue

Treating Postpartum Hemorrhage
Postpartum hemorrhage is usually taken very seriously. If you are suffering from this type of bleeding, you will likely be treated in hospital. Treatment includes:

  • uterine massage to stimulate contractions and stop blood flow
  • the medication Pitocin, which stimulates uterine contractions
  • the removal of excess placenta, typically by hand to prevent further bleeding
  • blood transfusion (if there is massive blood loss)
  • hysterectomy (if there is damage to the uterus)

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Postpartum Depression and Anxiety Effective assessment and teatment http://www.dolatbolandi.com/


http://www.parents.com/pregnancy/my-baby/cord-blood-banking/the-cord-blood-controversy/
Excerpt:
The Cord Blood Controversy
Given the chance to freeze their newborn's own stem cells, more and more expectant parents are signing up with pricey cord-blood banks. But could these cells really save your child's life someday?

Insurance -- or Reassurance? When Tracey and Victor Dones's 4-month-old son was diagnosed with osteopetrosis, a potentially fatal disorder that affects bone formation, the panic-stricken couple was relieved to hear that a stem-cell transplant could save his life. "We'd paid to store Anthony's umbilical-cord blood in a private bank in case he ever needed it -- and I thought we were so smart for having had the foresight to do that," says Tracey.
The Doneses were shocked, however, when doctors told them that Anthony's cord blood couldn't be used because the cells contained the same genetic defect that caused his condition. "The materials provided by the bank said this was Anthony's life insurance and could save him if he needed it. They never mentioned that the cells could be diseased. We felt duped," Tracey says. The Long Island, New York, couple has since filed a lawsuit against the bank alleging false advertising and consumer fraud.
They aren't the only ones questioning the business practices of private cord-blood banks. Both the American College of Obstetricians and Gynecologists (ACOG) and the American Academy of Pediatrics (AAP) issued statements in the late 1990s opposing the use of for-profit banks -- and criticizing their marketing tactics. Instead, they recommended that parents donate cord blood to public banks, which make it available for free to anyone who needs it. Globally, other organizations have done the same. Italy and France have banned private cord-blood banking altogether.
"Raising a family is expensive enough," says Jeffrey Ecker, MD, director of obstetrical clinical research at Massachusetts General Hospital, in Boston, and a member of ACOG's ethics committee. "There's no reason for parents to take on this additional financial burden when there's little chance of a child ever using his own cord blood."


http://en.wikipedia.org/wiki/Saprophytic
Excerpt:
Saprotrophic nutrition (pronounced /sæprɵˈtrɒfɪk/) is a process of chemoheterotrophic extra-cellular digestion involved in the processing of dead or decayed organic matter which occurs in saprotrophs or heterotrophs, and is most often associated with fungi, for example Mucor and Rhizopus. The process is most often facilitated through the active transport of such materials through endocytosis within the internal mycelium and its constituent hyphae.[1]

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601996/

http://www.hindu.com/seta/2005/11/24/stories/2005112400101500.htm
Excerpt:


Haunted Heart Susannah McCorkle
http://www.youtube.com/watch?v=5Ue4i9oBwVM  (dedicated to my heart throb, you know who you are ...cal )
Uploaded by on Apr 9, 2011
Susannah McCorkle with Dick Oatts Tenor Saxophone
and Allen Farnham Piano. From the album Hearts and Minds.

The People That You Never Get To Love
http://www.youtube.com/watch?v=zTD8UFQJZck&NR=1

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